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Although clinical data do not identify a pharmacokinetic interaction between bupropion and alcoholthere have been rare reports of adverse neuropsychiatric events or reduced alcohol tolerance in patients drinking alcohol during Zyban treatmentThe consumption of alcohol during Zyban treatment should be minimised or avoided.

Side effects include dry mouth and trouble sleepingbut these problems tend to go away after you take bupropion for about a weekYou might also have anxietyconstipationskin irritationor dizziness.

In patients receiving medicinal products known to lower the seizure thresholdZyban must only be used if there is a compelling clinical justification for which the potential medical benefit of smoking cessation outweighs the increased risk of seizuresee section 4.4

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